Viral load dynamics and disease severity in patients ...
Apr 21, 2020· Objective To evaluate viral loads at different stages of disease progression in patients infected with the 2019 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the first four months of the epidemic in Zhejiang province, China. Design Retrospective cohort study. Setting A designated hospital for patients with covid-19 in Zhejiang province, China.
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Risk of severe maternal morbidity or death in relation to ...
For example, at an A1c of 5.8% (the threshold for prediabetes), the probability of SMM or death was 2.2%, while at an A1c of 6.4% (the threshold for DM), the probability was 2.6%—each considerably higher than the overall population risk of 1.7% . This underscores the importance of identifying women with any degree of prepregnancy ...
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Anemia and end-stage renal disease in patients with type 2 ...
Anemia and end-stage renal disease in patients with type 2 diabetes and nephropathy. Mohanram A(1), Zhang Z, Shahinfar S, Keane WF, Brenner BM, Toto RD. Author information: (1)UT Southwestern Medical Center, Dallas, Texas 75390-8856, USA. BACKGROUND: Diabetic nephropathy is the leading cause of end-stage renal disease (ESRD).
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Controlling Type 2 Diabetes - HbA1c, Blood Sugar Testing ...
Apps, education and services Diabetes Forum App Find support, ask questions and share your experiences with 315,007 members of the diabetes community. Recipe App Delicious diabetes recipes, updated every Monday. Filter recipes by carbs, calories and time to cook. Low Carb Program Join 430,000 people on the award-winning education program for people with type 2 diabetes, prediabetes …
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Effects of Acute Insulin-Induced Hypoglycemia on Indices ...
OBJECTIVE To examine the effects of acute insulin-induced hypoglycemia on inflammation, endothelial dysfunction, and platelet activation in adults with and without type 1 diabetes. RESEARCH DESIGN AND METHODS We studied 16 nondiabetic adults and 16 subjects with type 1 diabetes during euglycemia (blood glucose 4.5 mmol/l) and hypoglycemia (blood glucose 2.5 mmol/l).
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Effectiveness of Dapagliflozin for Weight Loss - Full Text ...
May 30, 2019· This has been tested in patients with type 2 diabetes in which induces a weight loss of 2 to 3 kg and in combination with metformin even a weight loss up to 5.07 kg (-6.21 to 3.93 kg) without regain (at least for 2 years) as previously demonstrated.
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Characteristics and clinical applications of Wharton’s ...
Hu et al. Type 2 diabetes mellitus: 22: IV and intrapancreatic endovascular: 1 × 10 6 cells/kg b.w. for each route (P4-P6) HbA1c, fasting glucose, postprandial blood glucose, daily dosage of insulin and hypoglycaemic drugs, systematic inflammation and T lymphocyte count reduced. C-peptide and β-cell function improved. Liu et al. Type 2 ...
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Aliskiren Trial in Type 2 Diabetes Using Cardio-Renal ...
Aliskiren Trial in Type 2 Diabetes Using Cardio-Renal Endpoints (ALTITUDE): rationale and study design. Parving HH(1), Brenner BM, McMurray JJ, de Zeeuw D, Haffner SM, Solomon SD, Chaturvedi N, Ghadanfar M, Weissbach N, Xiang Z, Armbrecht J, Pfeffer MA.
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Addison's disease in type 1 diabetes presenting with ...
An association with type 1 diabetes is well recognised with 10%–18% of patients with Addison's disease also having insulin dependent diabetes.3 4 However, the prevalence of Addison's disease in type 1 diabetes is reported to be lower at 1.2%.5 Diabetes precedes the development of adrenocortical insufficiency in most patients, and often ...
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Targeting GLP-1 receptor trafficking to improve agonist ...
Apr 23, 2018· Drucker, D. J. et al. Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study. Lancet 372 , 1240–1250 (2008).
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Atrial Fibrillation and Diabetes Mellitus | Circulation ...
Apr 18, 2019· See Article by Fangel et al. Atrial fibrillation (AF) is the most common sustained arrhythmia worldwide and represents a major health burden affecting an estimated 33 million individuals and climbing. 1 The development of AF is multifactorial in etiology with age, , genetics, race, and comorbid conditions such as smoking, obesity, and diabetes mellitus playing a role. 2 Diabetes mellitus ...
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Comparator-Controlled Study for EGFR(+) Patients With ...
Jan 14, 2015· Comparator-Controlled Study for EGFR(+) Patients With Multiple BMs From NSCLC (BROKE) (EGFR-epidermal Growth Factor Receptor;BM-brain Metastases) (EGFR) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators.
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Canagliflozin and Stroke in Type 2 Diabetes Mellitus | Stroke
Introduction. The prevalence of type 2 diabetes mellitus has doubled over the past 3 decades and is likely to affect a half a billion people in the next 3 decades. 1 Given that new medications for diabetes mellitus could potentially be given to some tens of millions of people, it is vital that these medications are safe, and in particular, not associated with an increased vascular risk. 2,3 ...
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Hydroxycitric Acid:Uses, Side Effects, Dosage ...
Sep 17, 2019· Lim K, Ryu S, Ohishi Y, et al. Short-term (-)-hydroxycitrate ingestion increases fat oxidation during exercise in athletes. J Nutr Sci Vitaminol (Tokyo) 2002;48(2):128-133. View abstract. Loe YC, Bergeron N, Rodriguez N, Schwarz JM. Gas chromatography/mass spectrometry method to quantify blood hydroxycitrate concentration.
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Use of sodium-glucose co-transporter 2 inhibitors and risk ...
Apr 29, 2020· Introduction. Type 2 diabetes is the leading cause of kidney failure.1 Although treatment with angiotensin converting enzyme inhibitors and angiotensin receptor blockers reduces the risk of adverse renal outcomes in patients with diabetes,2 3 4 the risk remains high and a large need exists for new treatments that lower the risk of kidney failure. Sodium-glucose co-transporter 2 (SGLT2 ...
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Diabetes and exercise: When to monitor your blood sugar ...
Dec 20, 2018· Diabetes and exercise: Prevent problems by checking blood sugar before, during and after exercise. COVID-19 updates See how we're providing safe in-person care and virtual visits
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A Network Analysis of Biomarkers for Type 2 Diabetes ...
Numerous studies have investigated individual biomarkers in relation to risk of type 2 diabetes. However, few have considered the interconnectivity of these biomarkers in the etiology of diabetes as well as the potential changes in the biomarker correlation network during diabetes development. We conducted a secondary analysis of 27 plasma biomarkers representing glucose metabolism ...
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Highly efficient luminescence from space-confined charge ...
Jun 15, 2020· Sky-blue OLEDs employing one of these emitters achieve an external quantum efficiency (EQE) of 27.4% at 67 cd m−2 with only minor efficiency roll …
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Long-term risk of type 2 diabetes mellitus in relation to ...
Results. We documented 259 incident cases of type 2 diabetes during up to 18 years of follow-up. The adjusted HRs of type 2 diabetes associated with each 1 kg/m 2 increase in BMI were 1.16 (95% CI 1.12, 1.19) for baseline BMI and 1.16 (95% CI 1.13, 1.20) for most recent BMI. Moreover, each 5 kg increment of weight gain after GDM development was associated with a 27% higher risk of type 2 ...
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Insulin Secretion in Diabetes Mellitus - PubMed
A brief review of the normal physiology of insulin secretion is given. The dual role of glucose to directly stimulate insulin release and to potentiate insulin secretion to other islet regulators is emphasized. The B cell of the pancreatic islet is discussed as a metabolic integrator for nutrients, …
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Sugar and Type 2 diabetes | British Medical Bulletin ...
Two small studies in Type 1 and Type 2 diabetic subjects reported no significant effect on glycaemia including 22% EI in meals as sucrose. 35, 36 In a 12-month isocaloric crossover study, Osei et al. 37 found no evidence to suggest sugars were particularly harmful in adults with poorly controlled diabetes. In fact, glucose control was improved ...
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Association between high serum total cortisol ...
COVID-19 (p<0·0001) (appendix p 2). Median cortisol concentration in the group of patients with COVID-19 was 619 nmol/L [IQR 456–833] versus 519 nmol/L [378–684] in the patient group who did not have COVID-19 (p<0·0001) (appendix p 2). Univariable analysis of the group of patients with COVID-19 by Cox proportional hazards regression
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Hydroxycitric Acid: Health Benefits, Uses, Side Effects ...
Sep 17, 2019· Hydroxycitric acid is POSSIBLY SAFE for most people when taken by mouth for 12 weeks or less. Hydroxycitric acid can cause nausea, digestive tract discomfort, and headache when used short-term. Long-term safety is unknown. Special Precautions & Warnings: Pregnancy and breast-feeding: Not enough is known about the use of hydroxycitric acid during pregnancy and breast-feeding.
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Effects of Losartan on Renal and Cardiovascular Outcomes ...
Lewis EJ, Hunsicker LG, Clarke WR, et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001 ;345: 851 - 860
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Evidence Against an Important Role of Plasma ... - Diabetes
Sodium–glucose cotransport 2 inhibitors (SGLT2i) lower plasma glucose but stimulate endogenous glucose production (EGP). The current study examined the effect of dapagliflozin on EGP while clamping plasma glucose, insulin, and glucagon concentrations at their fasting level. Thirty-eight patients with type 2 diabetes received an 8-h measurement of EGP ([3-3H]-glucose) on three occasions.
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Lipoprotein Particle Size and Concentration by ... - Diabetes
May 01, 2010· OBJECTIVE Diabetic dyslipoproteinemia is characterized by low HDL cholesterol and high triglycerides. We examined the association of lipoprotein particle size and concentration measured by nuclear magnetic resonance (NMR) spectroscopy with clinical type 2 diabetes. RESEARCH DESIGN AND METHODS This was a prospective study of 26,836 initially healthy women followed for 13 years …
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Diabetes - Wikipedia
Diabetes mellitus (DM), commonly known as diabetes, is a group of metabolic disorders characterized by a high blood sugar level over a prolonged period of time. Symptoms often include frequent urination, increased thirst, and increased appetite. If left untreated, diabetes can cause many complications. Acute complications can include diabetic ketoacidosis, hyperosmolar hyperglycemic state, or ...
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MSX2 Antibody (NBP1-85445): Novus Biologicals
Wirrig EE, Hinton RB, Yutzey KE et al. Differential expression of cartilage and bone-related proteins in pediatric and adult diseased aortic valves. J Mol Cell Cardiol 2011 Mar [PMID: 21163264] Mulder J, Bjorling E, Jonasson K et al. Tissue profiling of the mammalian central nervous system using human antibody-based proteomics.
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Association of Ketone Body Levels With ... - Diabetes
We investigated the association of the levels of ketone bodies (KBs) with hyperglycemia and with 62 genetic risk variants regulating glucose levels or type 2 diabetes in the population-based Metabolic Syndrome in Men (METSIM) study, including 9,398 Finnish men without diabetes or newly diagnosed type 2 diabetes. Increasing fasting and 2-h plasma glucose levels were associated with elevated ...
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The Effect of Angiotensin-Converting-Enzyme Inhibition on ...
Among the 405 patients who had 2 or more determinations of serum creatinine (median, 13 determinations; maximum, 27) during an average follow-up of 2…
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